Definition

Hemoglobin A1c (HbA1c) is a specific type of hemoglobin that becomes chemically bonded to glucose in the bloodstream. This process allows HbA1c levels to serve as a marker for how much glucose has been circulating in the blood over the past 2 to 3 months.

Because of this, HbA1c is an important tool used in diagnosing diabetes and prediabetes, and it’s also crucial for monitoring how well people with diabetes are managing their blood sugar over time

Why is HbA1c an important indicator of diabetes?

High HbA1c levels indicate poor blood sugar control, which increases the risk of developing complications such as cardiovascular disease, kidney damage, nerve damage, and vision problems in people with diabetes.

For most people with diabetes, a target HbA1c level is usually less than 7%. However, this target may vary depending on individual factors like age, type of diabetes, and comorbidities. Managing HbA1c effectively can help reduce the risk of diabetes-related complications.

How is HbA1c measured and what are the typical ranges?

HbA1c is typically measured through a blood test, and in our case, it is measured using innovative technology involving a dry blood card. A single drop of blood is placed on the specially designed paper, where it dries.

Ranges are as follows:

  • Normal range: Less than 42 mmol/mol (equivalent to less than 6.0% in percentage).

  • Pre-diabetes (Increased risk): Between 42 mmol/mol and 47 mmol/mol (equivalent to 6.0% to 6.4% in percentage).

  • Diabetes: 48 mmol/mol or higher (equivalent to 6.5% or higher in percentage).

Factors that affect HbA1c levels

Certain medical conditions or factors can affect HbA1c levels and make them misleading. For example, anemia, chronic kidney disease, or variations in red blood cell lifespan can affect the accuracy of the test.

Some medications, like those used to treat malaria or high blood pressure, can also affect the HbA1c test.

Diet and Lifestyle: Poor diet, lack of exercise, and being overweight can all contribute to elevated HbA1c levels.

Prevalence of Diabetes and HbA1c in the UK

As of recent estimates, approximately 4.9 million people in the UK are living with diabetes, and around 13.6 million adults are at risk of developing type 2 diabetes due to factors like poor diet, sedentary lifestyle, and obesity.

The NHS spends billions annually on diabetes-related care, and improving HbA1c management is a critical area of focus to reduce long-term healthcare costs and improve the quality of life for those affected.

In the UK, routine HbA1c testing is key for early diagnosis and better management of diabetes, helping to mitigate risks and avoid complications. Regular check-ups and lifestyle changes can play a significant role in managing the disease.

More resources, at glance

For curious minds interested in exploring more about published resources and learning about the latest insights into diabetes management with our dry blood card, we encourage you to visit the site below.

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